Trental 400 mg, Uses, Side Effects, and Precautions

In this article, you are going to explore:

What Trental is and what it is used for?
Before you take Trental?
How to take Trental?
Possible Side Effects?
How to store Trental?
Furthur Information about Trental?

trental 400

What Trental is and what it is used for?

Trental contains a medicine called pentoxifylline. This belongs to a group of medicines called peripheral vasodilators. It works by increasing the blood flow to the arms and legs.

Trental can be used to treat:

Peripheral vascular disease (poor circulation to the arms and legs).
Intermittent claudication (pain on walking or at rest caused by poor circulation to the legs).

Before you take Trental:

Don’t take Trental if:

You are allergic (hypersensitive) to pentoxifylline, other similar medicines such as theophylline or aminophylline or to any of the other ingredients of Trental .Signs of an allergic reaction include: a rash, swallowing or breathing problems, swelling of your lips, face, throat or tongue
You have heart problems or have recently had a heart attack.
You have severe palpitations (very fast and uneven heartbeats).
You have had a stroke with bleeding in the brain (cerebral haemorrhage).
You have had bleeding in the eye (retinal haemorrhage).
Do not take this medicine if any of the above apply to you. If you are not sure, talk to your doctor or pharmacist before taking Trental. Take special care with Trental.

Check with your doctor or pharmacist before taking your medicine if:

You feel dizzy, light-headed or faint when you stand or sit up too quickly (hypotension).
You have problems with the blood supply to your heart caused by hardening or narrowing of the arteries.
You have liver or kidney problems If you are not sure if any of the above apply to you, talk to your doctor or pharmacist before taking Trental.

Taking other medicines:

Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines. This includes medicines you buy without a prescription, including herbal medicines. This is because Trental can affect the way some other medicines work. Also some medicines can affect the way Trental works.

In particular, tell your doctor if you are taking any of the following:

Trental may increase the effect of the following medicines:

Medicines for diabetes including tablets or insulin.
Medicines for high blood pressure.
Anticoagulants such as warfarin.

When take with Trental, the following medicines increase the chance of you getting side effects:

Ketorolac used for pain relief.
Theophylline used to treat wheezing or difficulty in breathing.
Ciprofloxacin used to treat bacterial infections.
Medicines used to stop blood clots from forming.
Cimetidine used to treat heartburn and stomach ulcers.
Taking Trental with food and drink.
Take Trental with or just after meals.

Pregnancy and breast-feeding:

You should not take Trental if you are pregnant. Ask your doctor or pharmacist for advice before taking any medicine. If you are breast-feeding or planning to breast-feed, talk to your doctor or pharmacist before taking Trental. This is because very small amounts may pass into the mothers’ milk.

Driving and using machines:

You may feel dizzy while taking this medicine. In this If this happens, do not drive or use any tools or machines.

How to take Trental:

Always take Trental exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure.

Taking this medicine:

If you feel the effect of your medicine is too weak or too strong, do not change the dose yourself, but ask your doctor.
Take this medicine by mouth.
Swallow the tablets whole with a drink of water.
Take with or just after a meal.

Adults including the elderly:

The usual starting dose is 1 tablet (400mg) three times a day. Your doctor may lower your dose to 1 tablet twice a day.

Patients with kidney problems:

Your doctor may give you a lower dose if necessary.

Children:

Trental is not suitable for use in children.

If you take more Trental than you should:

If you take more tablets than you should, talk to a doctor or go to a hospital straight away. The following effects may happen: low blood pressure, feeling sleepy, fits (seizures) or uneven heartbeat.

If you forget to take Trental:

Do not take a double dose to make up for a forgotten tablet.

If you stop taking Trental:

Keep taking Trental until your doctor tells you to stop taking it. If you have any further questions on the use of this product, ask your doctor or pharmacist.

Possible Side Effects:

Like all medicines, Trental can cause side effects, although not everybody gets them.

Stop taking Trental and see your doctor or go to a hospital straight away if;

If you have an allergic reaction. The signs may include: a rash, swallowing or breathing problems, swelling of your lips, face, throat or tongue
Bleeding under the skin.
Blood in your vomit or stools (motions).
If you develop a condition called aseptic meningitis. Signs include headache, neck stiffness, eye pain or discomfort in bright light.

Tell your doctor as soon as possible if you have any of the following side effects:

You bruise more easily than usual. This could be because of a blood disorder (thrombocytopenia).
Increased or fast heart beat (tachycardia).
Chest pain (angina).
Irregular heart beat (palpitations).
Frequent infections such as fever, severe chills, sore throat or mouth ulcers. These could be signs of a blood problem called ‘leukopenia’.
You get more infections than usual. This could be caused by a decrease in the number of white blood cells (neutropenia)

Tell your doctor or pharmacist if any of the following side effects gets serious or lasts longer than a few days. Also tell them if you notice any side effects not listed here:

Feeling sick (nausea) or being sick (vomiting), diarrhoea.
Headache, feeling dizzy, light-headed or faint.
Flushing
Feeling agitated, sleep problems.
An illness where the removal of bile from the liver is blocked (intrahepatic cholestasis). Sign include jaundice, rash or fever, and the colour of your water (urine) becomes darker.
Discomfort or bloating in the abdomen.
Rash.
Constipation.
Producing more saliva than usual.

Blood tests:

Trental can change the levels of liver enzymes shown up in blood tests. This can mean that your liver is not working properly.

How to store Trental:

Keep out of the reach and sight of children. Do not use Trental after the expiry date which is stated on the carton after EXP. The expiry date refers to the last day of that month.
Do not use Trental if you notice your tablets rare crumbling, broken or discoloured.
Do not store above 25°C. Store in the original package. Medicines should not be disposed of via wastewater or household waste. Ask your ur pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

Further Information:

What Trental contains:

Each tablet contains 400mg of the active substance, pentoxifylline
The other ingredients are Hydroxyethyl cellulose, povidone K 25, talc, magnesium stearate (Ph.Eur.) [plant-based], hypromellose, titanium dioxide (E171), erythrosine (E127), macrogol 8000.

FAQs:

What is Trental 400mg used for?
How does Trental 400mg work?
What are the common side effects of Trental 400mg?
Who should not take Trental 400mg?
How should I take Trental 400mg tablets?
Can I take Trental 400mg with other medications?
What should I do if I miss a dose of Trental 400mg?
What are the possible serious side effects of Trental 400mg?
How long does it take for Trental 400mg to show effects?
Can pregnant or breastfeeding women take Trental 400mg?
What should I avoid while taking Trental 400mg?
How should Trental 400mg be stored?
Can Trental 400mg cause allergic reactions?
Is Trental 400mg suitable for children?
Can I drink alcohol while taking Trental 400mg?
What should I do in case of an overdose of Trental 400mg?
Can Trental 400mg affect my ability to drive or operate machinery?
Are there any dietary restrictions while taking Trental 400mg?
How does Trental 400mg interact with blood thinners?
Can Trental 400mg be used for conditions other than those prescribed by a doctor?

Disclaimer!

Mediebook does not provide medical advice, treatment, or diagnoses. The information given here is for informational purposes only, and it should not be used as a replacement for the advice of a qualified doctor or physician.